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Tuesday, 8 November 2011

Life History of Charles Robert Darwin

Charles Robert Darwin (12 February 1809 – 19 April 1882) was an English naturalist. He established that all species of life have descended over time from common ancestry, and proposed the scientific theory that this branching pattern of evolution resulted from a process that he called natural selection.

He published his theory with compelling evidence for evolution in his 1859 book On the Origin of Species, overcoming scientific rejection of earlier concepts of transmutation of species. Darwin's early interest in nature led him to neglect his medical education at the University of Edinburgh; instead, he helped to investigate marine invertebrates. Studies at the University of Cambridge encouraged his passion for natural science. His five-year voyage on HMS Beagle established him as an eminent geologist whose observations and theories supported Charles Lyell's uniformitarian ideas, and publication of his journal of the voyage made him famous as a popular author.
Childhood of Darwin:
 In 1817Darwin attended Mr. Case's grammar school in Shrewsbury. He was a rather shy and reserved boy who invented wild stories, and showed off his athletic skills to the other boys. Darwin's mother, Susannah, died when he was eight years old. Darwin was referred to as "Bobby" by his family during his childhood. He and his brother setup a chemistry lab in the tool shed of the garden. Darwin enjoyed chemistry a great deal and it was during this time that he learned the basic principles of scientific experimentation. Darwin's father took him out of Shrewsbury school due to his poor grades and his having no direction in life. It is ironic to think that at this time his father castigated Darwin for his idleness, claiming that if he carried on this way he would end up being a disgrace to himself and his family. Apparently Darwin cared for nothing but shooting birds, playing with dogs, and catching rats.

Eager that Darwin should not "go astray" his father decided that his son will pursue a medical career as he and his grandfather did before him. Darwin was sent to the University of Edinburgh in Scotland, known as having one of the best medical schools in all of Europe. 
Overwork, illness, and marriage  
While developing this intensive study of transmutation, Darwin became mired in more work. Still rewriting his Journal, he took on editing and publishing the expert reports on his collections, and with Henslow's help obtained a Treasury grant of £1,000 to sponsor this multi-volume Zoology of the Voyage of H.M.S. Beagle, a sum equivalent to about £75,000 in 2009. He stretched the funding to include his planned books on geology, and agreed unrealistic dates with the publisher. As the Victorian era began, Darwin pressed on with writing his Journal, and in August 1837 began correcting printer's proofs.
 
 Darwin's health suffered from the pressure. On 20 September he had "an uncomfortable palpitation of the heart", so his doctors urged him to "knock off all work" and live in the country for a few weeks. After visiting Shrewsbury he joined his Wedgwood relatives at Maer Hall, Staffordshire, but found them too eager for tales of his travels to give him much rest. His charming, intelligent, and cultured cousin Emma Wedgwood, nine months older than Darwin, was nursing his invalid aunt. His uncle Jos pointed out an area of ground where cinders had disappeared under loam and suggested that this might have been the work of earthworms, inspiring "a new & important theory"on their role in soil formation which Darwin presented at the Geological Society.
on 1 November.
He strain took a toll, and by June he was being laid up for days on end with stomach problems, headaches and heart symptoms. For the rest of his life, he was repeatedly incapacitated with episodes of stomach pains, vomiting, severe boils, palpitations, trembling and other symptoms, particularly during times of stress such as attending meetings or making social visits. The cause of Darwin's illness remained unknown, and attempts at treatment had little success.


Colour Blindness in Human beings
Color blindness or color vision deficiency is the inability or decreased ability to see color, or perceive color differences, under lighting conditions when color vision is not normally impaired. "Color blind" is a term of art; there is no actual blindness but there is a fault in the development of either or both sets of retinal cones that perceive color in light and transmit that information to the optic nerve. The gene that causes color blindness is carried on the X chromosome, making the handicap more common among men (who have just one X chromosome) than among women.
Color blindness can be inherited. It is most commonly inherited from mutations on the X chromosome but the mapping of the human genome has shown there are many causative mutations – mutations capable of causing color blindness originate from at least 19 different chromosomes and 56 different genes.
Types:
There are many types of color blindness. The most common are red–green hereditary photoreceptor disorders, but it is also possible to acquire color blindness through damage to the retina, optic nerve, or higher brain areas. Acquired color blindness is generally unlike the more typical genetic disorders. For example, it is possible to acquire color blindness only in a portion of the visual field but maintain normal color vision elsewhere. Some forms of acquired color blindness are reversible. Transient color blindness also occurs (very rarely) in the aura of some migraine sufferers.
Red-green color blindness
This term combines four different types of color blindness. Protanomaly and protanopia are caused by defective or even missing L-cones (long-wavelengths). In opposite defective or missing M-cones (medium-wavelengths) are the source of deuteranomaly or deuteranopia. The genes encoding the L- and M-cone photopigments are located side by side on the X chromosome. Because of the genes are highly homologous and adjacent to one another, recombinations between them is common and can lead to anomalous pigments.
Blue cone monochromacy
As this type of monochromacy is caused by a complete absence of L- and M-cones, blue cone monochromacy is encoded at the same place as red-green color blindness on the X chromosome.
Blue-yellow color blindness
Tritanomaly and tritanopia which are commonly referred to as blue-yellow color blindness are caused by defective or missing S-cones (short-wavelength). These photopigments are encoded in genes which reside on chromosome 7, an autosomal chromosome. This is why blue-yellow color blindness occures at the same rate on both sexes.
Rod monochromacy
The total loss of color vision is called rod monochromacy or complete achromatopsia. In this case the retina does not have any cone cells at all. It is known to be an autosomal recessive disease and can be provoked by different circumstances. Recent studies show that it can be encoded on chromosome 2 as well as on chromosome 8. Earlier studies assigned chromosome 14 to rod monochromacy but this could not be reconstructed.
Chromosomes Involved in Color Blindness
Human beings have 23 pairs of chromosomes. Out of these 23 pairs 22 are autosomal chromosomes which are equal in both sexes and encode body functions. Only one pair consists of two sex-chromosomes which are different for men and women. The 22 pairs of equal chromosomes are numbered from 1 through to 22. The sex-chromosomes are labeled with X and Y, whereas women carry the combination XX and men the combination XY. This all sums up in a total of 46 chromosomes which make the human genome.
Diagnosis
Example of an Ishihara color test plate.
The numeral "74" should be clearly visible to viewers with normal color vision. Viewers with dichromacy or anomalous trichromacy may read it as "21", and viewers with achromatopsia may not see numbers.
An Ishihara test image as seen by subjects with normal color vision and by those with a variety of color deficiencies.
The Ishihara color test, which consists of a series of pictures of colored spots, is the test most often used to diagnose red–green color deficiencies. A figure (usually one or more Arabic digits) is embedded in the picture as a number of spots in a slightly different color, and can be seen with normal color vision, but not with a particular color defect. The full set of tests has a variety of figure/background color combinations, and enable diagnosis of which particular visual defect is present. The anomaloscope, described above, is also used in diagnosing anomalous trichromacy.
Because the Ishihara color test contains only numerals, it may not be useful in diagnosing young children, who have not yet learned to use numerals. In the interest of identifying these problems early on in life, alternative color vision tests were developed using only symbols (square, circle, car).
Most clinical tests are designed to be fast, simple, and effective at identifying broad categories of color blindness. In academic studies of color blindness, on the other hand, there is more interest in developing flexible tests to collect thorough datasets, identify copunctal points, and measure just noticeable differences.
Problems:
Colour blind often confuse red and green items. For example, they may find it difficult to distinguish a Braeburn apple from a Granny Smith and in some cases, the red and green of a traffic light without other clues (for example, shape or location). The vision of dichromats may also be compared to images produced by a color printer that has run out of the ink in one of its three color cartridges (for protanopes and deuteranopes, the magenta cartridge, and for tritanopes, the yellow cartridge). Dichromats tend to learn to use texture and shape clues and so are often able to penetrate camouflage that has been designed to deceive individuals with color-normal vision.

Sunday, 6 November 2011

PMLN and IMRAN KHAN

After the rally of Pmln on 28 october 2011 in bhatti gate in lahore, there was a lot of pressure on Imran khan because he was claiming that "Now, Lahore is with him, not with Pmln".While Lahore is with Pmln since 1990.And in the last election, after returning of Nawaz shrief from London Pmln won 10 seats of Lahore and the difference between Pmln candidate and the 2nd number candidate is about 20000 to 50000.Now, if Imran khan wants to win he has to remove this gap,a difficult task.
Many people is thinking that Pti is becoming a thread for Pmln because Imran khan hold a remarkable jalsa on Minar-e-Pakistan and proving that he is becoming a third option.Is he really becoming a third option?, because holding a great jalsa doesn't guarntee his success in coming election.Imran khan is known as a cricketer ,as a social worker (shoukat khanam hospital), in his jalsa about 80% people were 18 to 30 years,means mostly they are student.Lahore as it is known as "city of colleges" .
The question arise here ,which is the party whose voters are going in Pti or is with Imran khan.I think many voters of PPP,PMLQ and JI are now seeing towards Imran khan and Pti is also becoming a thread for PPP,as ppp is the 2nd major party of Punjab and he is losing his 2nd position in Punjab more rapidly especially in central Punjab.Bhuttoism is going to finish especially in central Punjab.Pmln mostly voters are  silent and they dont't like to go in jalsa or rallies,and it is difficult to understand how many areas of Pmln is affected from Pti.
 If we see the incoming election, it will be a test for Imran khan.He has to nominate best candidates if he really wants to win,but at this time, it seems difficult to find out well known politician in his party. However,he claimed that about 40 good politicians are ready to join Pti,but at this time only Mian Azhar has joined Pti and secondly, Is Pti has good and experienced team as, Dr. A.Q. khan said that Pti does not has good team.Pti is criticized both big parties PPP and PMLN,Is this policy gives benefit to Pti?
On the otherhand if we see towards Pmln ,they has very well known and respectable politicians.They have good team as compared to all other parties in Pakistan and also they have a lot of experience for election.Nawaz shrief, at this time is thinking to take good candidates in his party rather than to make an allience with other parties .Many people is also thinking that 'a vote for Pti means a vote in Favour of Asif ali zardari.
Both Pmln and Pti has almost same agenda if they make an allience ,it will be good for both of them.


Saturday, 5 November 2011


How to get more traffic on your website or blog
When someone has make a website and think that how he can get money from it.For making money from website or blog he has to get more traffic for his website or blog.
Here i tell you one of the best method for getting high traffic:
First go to to the website socialmarker.com ,in this websit in the bookmarker form put the title,url of your website,text and tags (put maximum tags separated by commas).
Open another google.com page and write googlekeyword or googleadword here he can submit the keyword of his website or blog.He can also get the most tag from here.
Another free method is to go on this website  http://tabzi.com/mina&ad=1 registered here and see website and increase the traffic of your website .
Here i put only one method for increasing traffic shortly i put another method i you are still not understand tell me i shall help you




What to do when someone is free


When someone is free and he/she cannot understand how to spend his free time, here is some ideas which he/she can do
  • To watch TV
          drama/movies/sports/talk shows
  • To read books
  • To write about something
  • To start thinking about some new ideas
  • To cook
  • To use Internet